Background. With the advent of multiparameter flow cytometry (FC) it became possible simultaneously analyze normal and malignant plasma cells (PC) in multiple myeloma (MM) patients. There is some data that residual normal bone marrow plasma cells (nBMPC) is of prognostic signifi cance in plasma cells dyscrasias. There is no data about clinical value of immunophenotypically normal peripheral blood circulating plasma cells (nCPC).
